pde5抑制剂多少钱一盒

PDE5 inhibitor 42
Compound 42 in ref 1
CAS 936449-28-4


pde5抑制剂多少钱一盒

文章插图
C23H31N7O3MW 454.53
Purity: 99%
Soluble in DMSO to 100 mM
Biological Activity:
【pde5抑制剂多少钱一盒】Potent and selective phosphodiesterase type 5 (PDE5) inhibitor (IC50: 0.04 nM); PDE6/PDE5 and PDE11/PDE5 ratios to be 100x and 530x respectively; a second generation PDE5 inhibitor under investigation.
References:
MB Tollefson et al. 1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors. Bioorg. Med. Chem. Lett. 2010, 20(10), 3120-3124.
Chemical Name: 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid
Axon 1709 | PDE5 inhibitor | Axon Medchem | PDE 5 inhibitor compound 42
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